The GAP43 gene in neuroblasts is upregulated in response to cell
seeding density

Mikiya Wakabayashi and Nakazawa N* (*Corresponding author)

microPublication Biology, 2025 Dec; doi: 10.17912/micropub.biology.001628

Nuclear enlargement after confined migration in cancer cells

Akane Iizuka and Nakazawa N* (*Corresponding author)

microPublication Biology, 2025 Nov; doi: 10.17912/micropub.biology.001623

FHL2 fused with biotin ligase shuttles between focal adhesions and the nucleus in a myosin II-dependent manner

Fujimoto Y, Fujimoto M, Konno D and Nakazawa N* (*Corresponding author)

microPublication Biology, 2025 Aug; doi: 10.17912/micropub.biology.001669

PIEZO1-dependent mode switch of neuronal migration in heterogeneous microenvironments in the developing brain

Nakazawa N*, Grenci G, Kameo Y, Takeda N, Sawada T, Kurisu J, Zhang Z, Toma K, Adachi T, Nonomura K, Kengaku M*. (*Corresponding author)

Cell Reports, 2025 Mar;44(3) doi: 10.1016/j.celrep.2025.115405

–Press release-

【Japanese】神経細胞が脳組織内の環境に応じて移動方法を使い分けることを発見 -神経細胞は空間の大きさを検知し、適した力を発動させる-（近畿大学）

【English】Squeezing through: understanding how neurons migrate through crowded brain tissue（Eurek Alert!, Kindai University）

–Media-

【Japanese】脳の神経細胞、環境に応じ移動使い分け　近畿大など解明（日刊工業新聞 2025年3月20日）、電子版および紙面

【English】Navigating the Maze: Insights into Neuronal Migration Through Dense Brain Tissue (bioengineer.org)

【English】New Insights into Neuronal Migration in Crowded Brain Environments (The Munich Eye)

Age-associated reduction of nuclear shape dynamics in excitatory neurons of the visual cortex

Frey T, Murakami T, Maki K, Kawaue T, Tani N, Sugai A, Nakazawa N, Ishiguro KI, Adachi T, Kengaku M, Ohki K, Gotoh Y, Kishi Y.

Aging cell, 2023 Sep;22(9):e13925. doi: 10.1111/acel.13925.

The Drosophila AWP1 ortholog Doctor No regulates JAK/STAT signaling for left-right asymmetry in the gut by promoting receptor endocytosis

Lai YT, Takeshi S, Kuroda J, Maeda R, Nakamura M, Hatori R, Ishibashi T, Taniguchi K, Ooike M, Taguchi T, Nakazawa N, Hozumi S, Okumura T, Aigaki T, Inaki M, Matsuno K.

Development, 2023 Mar 2:dev.201224. doi: 10.1242/dev.201224.

Combined Cohesin-Runx1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes

Ochi Y, Kon A, Sakata T, Nakagawa MM, Nakazawa N, Kakuta M, Kataoka K, Koseki H, Nakayama M, Morishita D, Tsuruyama T, Saiki R, Yoda A, Okuda R, Yoshizato T, Yoshida K, Shiozawa Y, Nannya Y, Kotani S, Kogure Y, Kakiuchi N, Nishimura T, Makishima H, Malcovati L, Yokoyama A, Takeuchi K, Sugihara E, Sato TA, Sanada M, Takaori-Kondo A, Cazzola M, Kengaku M, Miyano S, Shirahige K, Suzuki HI, Ogawa S.

Cancer Discovery, 2020 Jun;10(6):836-853. doi: 10.1158/2159-8290.CD-19-0982. Epub 2020 Apr 5.

Stopping transformed cancer cell growth by rigidity sensing

Yang B, Wolfenson H, Chung VY, Nakazawa N, Liu S, Hu J, Huang RY, Sheetz MP.

Nature Materials, Vol. 19, 239-250 (2020)

Chiral cell sliding drives left-right asymmetric organ twisting

Inaki M, Hatori R, Nakazawa N, Okumura T, Ishibashi T, Kikuta J, Ishii M, Matsuno K, Honda H.

eLife, Jun. 12;7 (2018)

Mechanotransmission and Mechanosensing of Human alpha-Actinin 1

Le S, Hu X, Yao M, Chen H, Yu M, Xu X, Nakazawa N, Margadant FM, Sheetz MP, Yan J.

Cell Reports, Vol. 21, No.10, 2714-2723 (2017)

Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression

Nakazawa N, Sathe AR, Shivashankar GV, Sheetz MP.

Proc. Natl. Acad. Sci. USA (PNAS), Vol.113, No.44, E6813-E6822 (2016)

–Press release-

【English】A Moving Story of FHL2 and Forces (Mechanobiology Institute, National University of Singapore)

【English】A Moving Story of FHL2 and Forces (EurekAlert!, National University of Singapore)

Cooperative Vinculin binding to Talin mapped by time resolved super resolution microscopy

Hu X, Jing C, Xu X, Nakazawa N, Cornish VW, Margadant FM, Sheetz MP.

Nano letters, Vol.16, No.7, 4062-4068 (2016)

Genetic analysis of Drosophila Class I Myosin genes in Left-Right asymmetric development

Okumura T, Sasamura T, Inatomi M, Hozumi S, Nakamura M, Hatori R, Taniguchi K, Nakazawa N, Suzuki E, Maeda R, Yamakawa T, Matsuno K.

Genetics, Vol.199, 1183-1199 (2015)

Left-right asymmetry is formed in individual cells by intrinsic cell chirality

Hatori R, Ando T, Sasamura T, Nakazawa N, Nakamura M, Taniguchi K, Hozumi S, Kikuta J, Ishii M, Matsuno K.

Mechanisms of Development, Vol.133, 146-162 (2014)

Reduced cell number in the hindgut epithelium disrupts hindgut left–right asymmetry in a mutant of , encoding a RhoGEF, in  embryos

Nakamura M, Matsumoto K, Iwamoto Y, Muguruma T, Nakazawa N, Hatori R, Taniguchi K, Maeda R, Matsuno K.

Mechanisms of Development, Vol.130, 169-180 (2013)

A novel Cre/loxP system for mosaic gene expression in the Drosophila embryo

Nakazawa N, Taniguchi K, Okumura T, Maeda R, Matsuno K.

Developmental Dynamics, Vol.241, 965-974 (2012)

Canonical Wnt signaling in the visceral muscle is required for left-right asymmetric development of the midgut

Kuroda J, Nakamura M, Yoshida M, Yamamoto H, Maeda T, Taniguchi K, Nakazawa N, Hatori R, Ishio A, Ozaki A, Shimaoka S, Ito T, Iida H, Okumura T, Maeda R, Matsuno K.

Mechanisms of Development, Vol.128, 625-639 (2012)

Deficient Notch signaling associated with neurogenic is compensated for by the unfolded protein response in Drosophila

Yamakawa T, Yamada K, Sasamura T, Nakazawa N, Kanai M, Suzuki E, Fortini ME, Matsuno K.

Development, Vol.139, 558-67 (2012)

Chirality in Planar cell shape contributes to left-right asymmetric epithelial morphogenesis

Taniguchi K, Maeda R, Ando T, Okumura T, Nakazawa N, Hatori R, Nakamura M, Hozumi S, Fujiwara H, Matsuno K.

Science, Vol.333, 339-341 (2011)

Left-right asymmetric morphogenesis of the anterior midgut depends on the activation of a non-muscle myosin II in Drosophila

Okumura T, Fujiwara H, Taniguchi K, Kuroda J, Nakazawa N, Nakamura M, Hatori R, Ishio A, Maeda R, Matsuno K.

Developmental Biology, Vol.344, 693-706 (2010)

Head region of unconventional Myosin I family members is responsible for the organ-specificity of their roles in left-right polarity in Drosophila

Hozumi S, Maeda R, Taniguchi-Kanai M, Okumura T, Taniguchi K, Kawakatsu Y, Nakazawa N, Hatori R, Matsuno K.

Developmental Dynamics, Vol.237, 3528-3537 (2008)

The roles of FHL2 as a mechanotransducer for cellular functions in the mechanical environment

Fujimoto Y and  Nakazawa N*(*Corresponding author)

Frontiers in Cell and Developmental Biology, 12:1431690. doi: 10.3389/fcell.2024.1431690 (2024)

Editorial: Multicellularity: Views from cellular signaling and mechanics

Hirata H, Nakazawa N, Hirashima T, Ravasio A.

Frontiers in Cell and Developmental Biology, 13:11:1172921 (2023)

Mechanical regulation of nuclear translocation in migratory neurons

Nakazawa N*, Kengaku M. (*Corresponding author)

Frontiers in Cell and Developmental Biology, 8:150 (2020)

Mechanostress-induced DNA damage in migrating neurons during brain development

Z. Zhang, A. Canela, P. Zou, T. Furuta, T. Kawaue, N. Nakazawa, M. Saeki, M. Utsunomiya, J. Kurisu, F. Ishidate, H. Sasanuma, Y. Kishi, M. Kengaku

Research Squre, 2025

Neuronal migration induces DNA damage in developing brain

Z. Zhang, A. Canela, P. Zou, T. Furuta, T. Kawaue, N. Nakazawa, M. Saeki, M. Utsunomiya, J. Kurisu, F. Ishidate, H. Sasanuma, Y. Kishi, M. Kengaku

bioRxiv, 2025

Migrating neurons adapt motility modes to brain microenvironments via a mechanosensor, PIEZO1

N. Nakazawa, G. Grenci, Y. Kameo, N. Takeda, T. Sawada, J. Kurisu, Z. Zhejing, T. Adachi, K. Nonomura, M. Kengaku

bioRxiv, 2023

Age-associated reduction of nuclear shape dynamics in excitatory neurons of the visual cortex

T. Frey, T. Murakami, K. Maki, T. Kawaue, A. Sugai, N. Nakazawa, T. Adachi, M. Kengaku, K. Ohki, Y. Gotoh, Y. Kishi

bioRxiv, 2022

The Drosophila AWP1 ortholog Doctor No regulates JAK/STAT signaling for left-right asymmetry in the gut by promoting receptor endocytosis

Y.T. Lai, T. Sasamura, J. Kuroda, R. Maeda, M. Nakamura, R. Hatori, T. Ishibashi, K. Taniguchi, M. Ooike. T. Taguchi, N. Nakazawa, S. Hozumi, T. Okumura, T. Aigaki, M. Inaki, K. Matsuno

bioRxiv, 2022

Stopping transformed cell growth with cytoskeletal proteins: Turning a Devil into an Angel

Bo Yang, H. Wolfenson, N. Nakazawa, S. Liu, J. Hu, M. P. Sheetz

bioRxiv, 2018

Multicellularity: Views from Cellular Signaling and Mechanics (Research topic e-book)

Hirata H., Ravasio A., Nakazawa N, Hirashima T.

Frontiers in Cell and Developmental Biology, e-book (2023)

カンデル神経科学（第２版）翻訳：第７章 神経系の細胞

中澤 直高、見学美根子