Publications / Grants

Combined Cohesin-Runx1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes

Y. Ochi, A. Kon, T. Sakata, M. M. Nakagawa, N. Nakazawa, M. Kakuta, K. Kataoka, H. Koseki, M. Nakayama, D. Morishita, T. Tsuruyama, R. Saiki, A. Yoda, R. Okuda, T. Yoshizato, Y. Shiozawa, Y. Nannya, S. Kotani, Y. Kogure, N. Kakiuchi, T. Nishimura, H. Makishima,  L. Malcovati, A. Yokoyama, K. Takeuchi, E. Sugihara, T. A. Sato, M. Sanada, A. Takaori-Kondo, M. Cazzola, M. Kengaku, S. Miyano, K. Shirahige, H. I. Suzuki, S. Ogawa

Cancer Discovery, 2020 Jun;10(6):836-853. doi: 10.1158/2159-8290.CD-19-0982. Epub 2020 Apr 5.

Stopping transformed cancer cell growth by rigidity sensing

Bo Yang, H. Wolfenson, V. Y. Chung,  N. Nakazawa, S. Liu, J. Hu, R. YJ. Huang,  M. P. Sheetz

Nature Materials, Vol. 19, 239-250 (2020)

Chiral cell sliding drives left-right asymmetric organ twisting

M. Inaki, R. Hatori,  N. Nakazawa, T. Okumura, T. Ishibashi, J. Kikuta, M. Ishii, K. Matsuno, H. Honda

eLife, Jun. 12;7 (2018)

Mechanotransmission and Mechanosensing of Human alpha-Actinin 1

S. Le, X. Hu, M. Yao, H. Chen, M. Yu, X. Xu, N. Nakazawa, F. M. Margadant, M.P. Sheetz, J. Yan

Cell Reports, Vol. 21, No.10, 2714-2723 (2017)

Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression

N. Nakazawa, A.R. Sathe, G.V. Shivashankar, and M.P. Sheetz

Proc. Natl. Acad. Sci. USA (PNAS), Vol.113, No.44, E6813-E6822 (2016)

Cooperative Vinculin binding to Talin mapped by time resolved super resolution microscopy

X. Hu, C. Jing, X. Xu, N. Nakazawa, V. W. Cornish, F. Margadant, M. P. Sheetz

Nano letters, Vol.16, No.7, 4062-4068 (2016)

Genetic analysis of Drosophila Class I Myosin genes in Left-Right asymmetric development

T. Okumura, T. Sasamura, M. Inatomi, S. Hozumi, M. Nakamura, R. Hatori, K. Taniguchi, N. Nakazawa, E. Suzuki, R. Maeda, T. Yamakawa, and K. Matsuno

Genetics, Vol.199, 1183-1199 (2015)

Left-right asymmetry is formed in individual cells by intrinsic cell chirality

R. Hatori, T. Ando, T. Sasamura, N. Nakazawa, M. Nakamura, K. Taniguchi, S. Hozumi, J. Kikuta, M. Ishii, K. Matsuno

Mechanisms of Development, Vol.133, 146-162 (2014)

Reduced cell number in the hindgut epithelium disrupts hindgut left–right asymmetry in a mutant of , encoding a RhoGEF, in  embryos

M. Nakamura, K. Matsumoto, Y. Iwamoto, T. Muguruma, N. Nakazawa, R. Hatori, K. Taniguchi, R. Maeda, K. Matsuno

Mechanisms of Development, Vol.130, 169-180 (2013)

A novel Cre/loxP system for mosaic gene expression in the Drosophila embryo

N. Nakazawa, K. Taniguchi, T. Okumura, R. Maeda, and K. Matsuno

Developmental Dynamics, Vol.241, 965-974 (2012)

Canonical Wnt signaling in the visceral muscle is required for left-right asymmetric development of the midgut

J. Kuroda, M. Nakamura, M. Yoshida, H. Yamamoto, T. Maeda, K. Taniguchi, N. Nakazawa, R. Hatori, A. Ishio, A. Ozaki, S. Shimaoka, T. Ito, H. Iida, T. Okumura, R. Maeda, K. Matsuno

Mechanisms of Development, Vol.128, 625-639 (2012)

Deficient Notch signaling associated with neurogenic is compensated for by the unfolded protein response in Drosophila

T. Yamakawa, K. Yamada, T. Sasamura, N. Nakazawa, M. Kanai, E. Suzuki, M. E. Fortini, and K. Matsuno

Development, Vol.139, 558-67 (2012)

Chirality in Planar cell shape contributes to left-right asymmetric epithelial morphogenesis

K. Taniguchi, R. Maeda, T. Ando, T. Okumura, N. Nakazawa, R. Hatori, M. Nakamura, S. Hozumi, H. Fujiwara, K. Matsuno

Science, Vol.333, 339-341 (2011)

Left-right asymmetric morphogenesis of the anterior midgut depends on the activation of a non-muscle myosin II in Drosophila

T. Okumura, H. Fujiwara, K. Taniguchi, J. Kuroda, N. Nakazawa, M. Nakamura, R. Hatori, A. Ishio, R. Maeda, K. Matsuno

Developmental Biology, Vol.344, 693-706 (2010)

Head region of unconventional Myosin I family members is responsible for the organ-specificity of their roles in left-right polarity in Drosophila

S. Hozumi, R. Maeda, M. T. Kanai, T. Okumura, K. Taniguchi, Y. Kawakatsu, N. Nakazawa, R. Hatori, and K. Matsuno

Developmental Dynamics, Vol.237, 3528-3537 (2008)

Mechanical regulation of nuclear translocation in migratory neurons

N. Nakazawa* and M. Kengaku (*Corresponding author)

Frontiers in Cell and Developmental Biology, 8:150 (2020)

Migrating neurons adapt motility modes to brain microenvironments via a mechanosensor, PIEZO1

N. Nakazawa, G. Grenci, Y. Kameo, N. Takeda, T. Sawada, J. Kurisu, Z. Zhejing, T. Adachi, K. Nonomura, M. Kengaku

bioRxiv, 2023

Age-associated reduction of nuclear shape dynamics in excitatory neurons of the visual cortex

T. Frey, T. Murakami, K. Maki, T. Kawaue, A. Sugai, N. Nakazawa, T. Adachi, M. Kengaku, K. Ohki, Y. Gotoh, Y. Kishi

bioRxiv, 2022

The Drosophila AWP1 ortholog Doctor No regulates JAK/STAT signaling for left-right asymmetry in the gut by promoting receptor endocytosis

Y.T. Lai, T. Sasamura, J. Kuroda, R. Maeda, M. Nakamura, R. Hatori, T. Ishibashi, K. Taniguchi, M. Ooike. T. Taguchi, N. Nakazawa, S. Hozumi, T. Okumura, T. Aigaki, M. Inaki, K. Matsuno

bioRxiv, 2022

Stopping transformed cell growth with cytoskeletal proteins: Turning a Devil into an Angel

Bo Yang, H. Wolfenson, N. Nakazawa, S. Liu, J. Hu, M. P. Sheetz

bioRxiv, 2018

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